Neutropenic Enterocolitis: Clinical Features and Outcomes

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Neutropenic Enterocolitis in a Woman

Patients who become neutropenic after getting combined chemotherapy are at special risk of developing neutropenic enterocolitis (also called typhlitis), a necrotizing inflammation of the cecum..1-10 In 1970, Wagner et al11 first described neutropenic enterocolitis in children with hematologic malignancies or aplastic anemia, but since then many adult cases have been reported.1,3-4,7-10,12 The c...

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Changing presentation and management of neutropenic enterocolitis.

OBJECTIVE To characterize the current clinical presentation and management of neutropenic enterocolitis. DESIGN Retrospective review of records of oncology unit patients requiring general surgical consultation for abdominal complaints in a 1-year period. SETTING Oncology unit of a tertiary care, university teaching hospital. PATIENTS AND INTERVENTIONS Fourteen patients diagnosed as having...

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Neutropenic enterocolitis and docetaxel neoadjuvant chemotherapy.

Neutropenic enterocolitis (NE, typhlitis) is a rare complication of intensive chemotherapy, and though it is more often observed in leukemia and lymphoma, there are a few reported cases of patients with lung cancer [1], hormone-refractory prostate cancer [2] and metastatic breast cancer [3]. Docetaxel, a taxane-based compound, has been proven to be a very effective treatment with acceptable tox...

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Chemotherapy-induced neutropenic necrotizing enterocolitis: a review.

Neutropenia is a common toxicity of systemic cytotoxic therapy. Neutropenic enterocolitis (NE) is a rare occurrence but can be fatal, subsequent to neutropenia. The exact incidence and frequency is difficult to establish, but is usually underestimated. It is often missed but has recently been appreciated with increasing frequency in solid tumours. NE was initially reported with taxenes but now ...

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Neutropenic enterocolitis (NE) or typhlitis is a serious complication of anticancer therapy, especially in hematological malignancies. We describe a case of acute lymphoid leukemia presenting the early onset of a syndrome with the clinical features and specific radiological findings of NE during the neutropenic phase.

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ژورنال

عنوان ژورنال: Blood

سال: 2014

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v124.21.5984.5984